SCID Mice

Inbred Mice

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Origin:
In1980, Bosma found the mutation in C.B-17/lcr mice which were from Fox Chase cancer center.

Colour: Glabrous, albino

Features:

(1)   Severe combined immunodeficiency (SCID)

(2)   Mutation on Chromosome 16 which is responsible for deficient activity of an enzyme involved in DNA repair

(3)   Impair the ability to make T or B lymphocytes, or activate some components of the complement system, and cannot fight infections, nor reject tumors and transplants efficiently

 

Ideal Research FieldsImmune system, cell transplantation strategies, virology, oncology, physiology, epidemiology, pathology of blood

Reference Data:

Mature Period (Male)

6-8 weeks

Mature Period (Female)

6-8 weeks

Mating Ratio

1:2

Estrus Cycle

3-5 days

Pregnancy

17-21 days

Average Litter Size

4-5 mice

Birth Weight

1-2g

Weaning Weight (Male)

9-12g

Weaning Weight (Female)

9-12g

Lactation

21 days

Average Feed Consumption

5g (per 100 g weight, per day)

Average Water Consumption

6-7 ml (per 100 g weight, per day)

Feeding Temperature

21±2

Relative Humidity

40-70%

Light Cycle

12/12 hour

Weight Loss During the Transit

10%

Ordering hotline: 020-81122060